梁斌,男,1981年生,五台人,中国共产党员,副主任医师,医学博士。美国托马斯杰弗逊大学博士后,首都医科大学首都医科大学附属北京安贞医院博士后,硕士生导师。山西省委组织部山西省“青年拔尖人才”。中国医师协会心血管分会“未来之星”,山西省高等学校优秀青年学术带头人,山西省高等学校“131领军人才”,山西医科大学第二医院“十佳青年”。
工作经历
美国汤玛斯·杰佛逊大学博士后
首都医科大学附属北京安贞医院博士后
2007年-至今,山西医科大学第二医院,主治医师
社会任职
梁斌目前担任中国整合医学心血管专业委员会委员,山西省高血压分会青年委员会副主任委员,山西省高血压分会常务委员,山西省心律失常青年委员会常务委员,山西省心血管病分会基层工作委员会委员,山西省医师协会房颤专业委员会委员,山西省心脑血管慢病防治专业委员会委员。
学术研究
梁斌教授承担了包括国家自然基金、山西省青年拔尖人才基金、山西省自然基金等科研项目,累计科研项目经费超过100万元。作为第一作者和通讯作者,他在SCI收录期刊上发表了10篇论文,并担任SCI收录期刊J Cell Physiol和Acta Biochimica et Biophysica Sinica的审稿人。梁斌教授的研究成果获得了山西省科技进步二等奖两项。
承担课题
梁斌教授承担的课题包括山西省高等学校青年学科带头人基金,研究项目涉及Ang-(1-7)对动脉粥样硬化的影响、MicroRNA-10a/b对胆固醇流出的影响、血管紧张素-(1-7)对动脉粥样硬化的保护作用及机制研究、miR-20a/b对胆固醇逆转运的影响等。
发表论文
[1] JingyiWang,Xu Wang, Bin Liang(Co-corresponding author). Curcumin inhibits the growth via Wnt/β-catenin pathway in non-small-celllung cancer cells. Eur Rev Med Pharmacol Sci, 2018, 22:7492-7499.(SCI,IF=2.387)
[2] Bin Liang,Ya-Nan Zhao, Xin Wang, Xiao-Jing Yu,Ying Li, Hui-Yu Yang, Qing Su, Yu-MingKang, Zhi-Ming Yang. Angiotensin-(1-7) attenuates hypertension and cardiachypertrophy via modulation of nitric oxide and neurotransmitterlevels in the paraventricular nucleus in salt-sensitive hypertensive rats.RSC Adv, 2018,8, 8779-8786.(SCI,IF=3.108)
[3] Liang B,Wang X, Song X, Bai R, Yang H, Yang Z, Xiao C, Bian Y. MicroRNA-20a/b regulatescholesterol efflux through post-transcriptional repression of 巴西网球公开赛bindingcassette transporter A1. Biochim Biophys Acta. 2017,1862(9):929-938.(SCI,IF=5.547)
[4] Liu GZ, Liang B, Lau WB, Wang Y, Zhao J, Li R, Wang X, Yuan Y, Lopez BL, ChristopherTA, Xiao C, Ma XL, Wang Y.High glucose/High Lipids impair vascular adiponectin 函数 via inhibition ofcaveolin-1/AdipoR1 signalsome formation. Free Radic Biol Med. 2015Oct 8;89:473-485. doi: 10.1016/j.free radbiomed.2015.09.005. (SCI,IF=5.736)
[5] Liang B, Wang X, Zhang NN, Yang HY,Bai R, Liu M, Bian YF, Xiao CS, Yang ZM. Angiotensin-(1-7) attenuatesAngiotensin II-induced ICAM-1, VCAM-1, and MCP-1 expression via the MASreceptor through suppression of P38 and NF-κB pathways in HUVECs. Cell PhysiolBiochem, 2015, 35:2472-2482.(SCI,IF=5.104)
[6] Liang B, Wang X, Guo X, Yang Z, BaiR, Liu M, Xiao C, Bian Y. Adiponectin upregulates ABCA1 expression throughliverX 捕手 alpha signaling pathway in RAW264.7 macrophages. Int J Clin ExpPathol, 2015, 8(1):450-457. (SCI,IF=1.891)
[7] Bin Liang, RuiBai, Yaoxia Han, xiaohong guo , chuanshi xiao, yunfei bian. Adiponectinupregulates ABCG1 experssion through LXRαsignalingpathway in RAW 264.7 macrophage. Progress in biochemistry and biophysics, 2015,42(9):850-857. (SCI, IF=0.324)
[8] LiangB, WangX, BianY, YangH, LiuM, BaiR, YangZ, XiaoC.Angiotensin-(1-7)upregulates expression of ABCA1 and ABCG1 through the Mas 捕手 via theliver X receptor alpha signaling pathway in THP-1 macrophages treated withAngiotensin II. Clin Exp Pharmacol Physiol, 2014,41(12):1023-1030.(SCI,IF=2.405)
[9] LiangB, WangX, YanF, BianYF, LiuM, BaiR, YangHY, ZhangNN, YangZM, Xiao计算机科学 Angiotensin-(1-7) upregulates (巴西网球公开赛binding cassette transporter A1)ABCA1 expression through cyclic AMP signaling pathway in RAW 264.7 macrophages.Eur Rev Med Pharmacol Sci, 2014, 18(7):985-991. (SCI,IF=1.213)
[10] Yueru Wang, Yingying Guo, Bin Liang (Co-corresponding author),Chuanshi Xiao. Effect of adiponectin on macrophage reverse cholesteroltransport in adiponectin-/- mice and its mechanism. Experimental andTherapeutic Medicine, 2017, 13:2757-2762. (SCI, IF=1.28)
[11] Wang ZC, Qi J, Liu LM, Li J, Xu HY,Liang B (Co-corresponding author),Li B. 缬沙坦 reduces AT1-AA-induced apoptosis through suppression oxidativestress mediated ER stress in endothelial progenitor cells. Eur Rev MedPharmacol Sci. 2017,21(5):1159-1168. (SCI,IF=2.387)
[12] Bin Liang, XinWang, Rui Bai, Hui Yang, Yaoxia Han, Zhiming Yang, Yunfei Bian, Chuanshi Xiao.MicroRNA-20a/b regulates cholesterol efflux through posttranscrip -tionalrepression of atpBinding Cassette Transporter A1 in THP-1 macrophage /RAW264.7-derived foam cells. J Am Coll Cardiol, 2015,66(16):SUPPL,C70.(Abstract, SCI,IF=17.759)
[13] Wang Y, Liang B,Lau WB, Du Y, Guo R, Yan Z, Gan L, Yan W, Zhao J, Gao E, Koch W, Ma XL.Restoring 糖尿病induced autophagic flux arrest in ischemic/reperfused heartby ADIPOR (adiponectin 捕手) activation involves both AMPK-dependent andAMPK-independent signaling. Autophagy. 2017;13(11):1855-1869.(SCI,IF=11.1)
参考资料
心律失常亚专科-山西医科大学第二医院.山西医科大学第二医院.2021-05-10
山西省卫生健康委员会网站-公示公告.山西卫计委.2021-05-10
心血管内科-山西医科大学第二医院.山西医科大学第二医院.2021-05-10
山西医科大学第二医院心血管内科.山西医科大学第二医院心血管内科.2024-03-14
Restoringdiabetes.National Library of Medicine.2024-03-14