郭俊明，男，1965年9月出生，汉族，江西省赣州市南康区人，中山医科大学生物化学与分子生物学专业博士毕业。
个人经历
教育背景
郭俊明于1965年出生于江西赣州南康，后毕业于中山医科大学，取得生物化学与分子生物学博士学位。
工作经历
郭俊明目前任职于宁波大学医学院，担任生物化学与分子生物学研究所所长。他还是浙江省“新世纪151人才工程”第二层次的人才，以及宁波市高校名师培养的对象。在教育方面，他是宁波大学生物化学与分子生物学硕士点的负责人，并且在上海交通大学医学院担任博士生导师。
近期研究成果
论文列表
郭俊明近期发表的重要论文包括：
1. Guo J, Jiang C, Wang Z, Lee HJ, Hu H, Malewicz B, Lee HJ, Lee JH, Baek NI, Jeong JH, Kim DK, Kang KS, Kim SH, Lu J. A novel class of pyranocoumarin anti-androgen receptor signaling compounds. Mol Cancer Ther. 2007;6(3):907-17. (SCI，IF 5.003)
2. Jiang C, Guo J, Wang Z, Xiao B, Lee HJ, Lee EO, Kim SH, Lu J. Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells. Breast Cancer Res. 2007;9(6):R77. （SCI，IF 5.052; Contributed equally）
3. Guo J*, Xiao B, Zhang X, Jin Z, Chen J, Qin L, Mao X, Shen G, Chen H, Liu Z. Combined use of positive and negative immunomagnetic isolation followed by real-time RT-PCR for detection of the circulating tumor cells in patients with colorectal cancers. J Mol Med. 2004;82(11):768-74. (SCI IF 4.37)
4. Xiao B, Guo J*, Miao Y, Jiang Z, Huan R, Zhang Y, Li D, Zhong J. Detection of miR-106a in gastric carcinoma and its clinical significance. Clin Chim Acta. 2009;400(1-2):97-102. （SCI IF 2.96）
5. Xiao B, Guo J*, Liu D, Zhang S. Aloe-emodin induces in vitro G2/M arrest and alkaline phosphatase activation in human oral cancer KB cells. Oral Oncol. 2007;43(9):905-10. （SCI IF 2.928）
6. Yao F, Guo JM*, Xu CF, Lou YL, Xiao BX, Zhou WH, Chen J, Hu YR, Liu Z, Hong GF. Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis. Clin Chim Acta. 2005;361(1-2):119-27. (SCI IF 2.96)
7. Guo J*, Miao Y, Xiao B, Huan R, Jiang Z, Meng D, Wang Y. Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. J Gastroenterol Hepatol. 2009;24(4):652-7. （SCI IF2.275）
8. Guo J*, Yao F, Lou Y, Xu C, Xiao B, Zhou W, Chen J, Hu Y, Liu Z. Detecting carcinoma cells in peripheral blood of patients with hepatocellular carcinoma by immunomagnetic beads and rt-PCR. J Clin Gastroenterol. 2007;41(8):783-8. （SCI IF 2.775）
9. Guo J*, Xiao B, Zhang S, Liu D, Liao Y, Sun Q. Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. Cancer Biol Ther. 2007;6(1):85-8. （SCI IF 2.761）
10. Guo J*, Xiao B, Lou Y, Yan C, Zhan L, Wang D, Zhao W. Antitumor effects of all-trans-retinoic acid on cultured human pancreatic cancer cells. J Gastroenterol Hepatol. 2006 Feb;21(2):443-8. （SCI IF 2.275）
11. Guo J*, Xiao B, Jin Z, Qin L, Chen J, Chen H, Zhang X, Liu Z. Detection of cytokeratin 20 mRNA in the peripheral blood of patients with colorectal cancer by immunomagnetic bead enrichment and real-time reverse transcriptase-polymeras chain reaction. J Gastroenterol Hepatol. 2005;20(8):1279-84. (SCI IF 2.275)
12. Guo JM*, Xiao BX, Liu DH, Grant M, Zhang S, Lai YF, Guo YB, Liu Q. Biphasic effect of daidzein on cell growth of human colon cancer cells. Food Chem Toxicol. 2004;42(10):1641-6. (SCI IF 2.321)
13. Guo J*, Xiao B, Liu Q, Gong Z, Le Y. Suppression of C-myc Expression Associates with Anti-Proliferation of Aloe-Emodin on Gastric Cancer Cells. Cancer Investigation, 2008 26:4, 369 – 374 （SCI IF1.976）
14. Guo JM*, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH. Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. Acta Pharmacol Sin. 2007 Dec;28(12):1991-5. （SCI IF 1.676）
15. Lu J, Kim SH, Jiang C, Lee H, Guo J. Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents. Acta Pharmacol Sin. 2007;28(9):1365-72. （SCI IF 1.676）
16. Xiao B, Guo J*, Lou Y, Meng D, Zhao W, Zhang L, Yan C, Wang D. Inhibition of growth and increase of alkaline phosphatase activity in cultured human oral cancer cells by all-trans retinoic acid. Int J Oral Maxillofac Surg. 2006;35(7):643-8. （SCI IF 1.487）
17. Guo JM*, Xiao BX, Kang GZ, Liu DH, Chen H, Zhang S, Zhang XN. Suppression of telomerase activity and arrest at G1 phase in human cervical cancer HeLa cells by all-trans retinoic acid. Int J Gynecol Cancer. 2006 Jan-Feb;16(1):341-6. （SCI IF 1.932）
18. Malewicz B, Wang Z, Jiang C, Guo J, Cleary MP, Grande JP, Lü J. Enhancement of mammary carcinogenesis in two rodent models by silymarin dietary supplements. Carcinogenesis. 2006;27(9):1739-47. （SCI，IF 4.93）
19. Jiang C, Lee HJ, Li GX, Guo J, Malewicz B, Zhao Y, Lee EO, Lee HJ, Lee JH, Kim MS, Kim SH, Lu J. Potent antiandrogen and androgen receptor activities of an Angelica gigas-containing herbal formulation: identification of decursin as a novel and active compound with implications for prevention and treatment of prostate cancer. Cancer Res. 2006 Jan 1;66(1):453-63. (SCI，IF 7.514)
20. Guo JM*, Kang GZ, Xiao BX, Liu DH, Zhang S. Effect of daidzein on cell growth, cell cycle, and telomerase activity of human cervical cancer in vitro. Int J Gynecol Cancer. 2004;14(5):882-8. (SCI IF 1.932)
专著列表
郭俊明近期发表的重要专著包括：
1. 郭俊明主编。人体基因学。杭州。浙江科技出版社.2004.
科研奖项
郭俊明近期获得的主要科研奖项包括：
1. 郭俊明、肖丙秀、刘东海、楼燕茹、赖依峰、张顺、刘琼、汪东辉、詹丽、严春红. 浙江省科学技术奖。用现代分子生物学技术阐明常见营养成分的抗癌机制.2008年度。三等奖.
2. 郭俊明、肖丙秀、张新军、陈健、楼燕茹、徐长风. 浙江省科技奖。外周血中微量消化系统恶性肿瘤细胞的分析及其临床应用.2006年度。三等奖.
3. 郭俊明、肖丙秀、张新军、陈健、楼燕茹、徐长风. 浙江省医药卫生科技创新奖。外周血中微量消化系统恶性肿瘤细胞的分析.2006年度。一等奖.
4. 郭俊明、肖丙秀、刘东海、赖依峰、张顺、刘琼. 浙江省高校科研成果奖。大豆苷原防治常见恶性肿瘤的研究.2007年度。一等奖.
5. 肖丙秀 郭俊明 楼燕茹 刘东海 汪东辉 詹丽 严春红. 宁波市科技进步奖。全反式维甲酸诱导分化实体瘤分子机制的系列研究.2008年度。三等奖.
参考资料
生物化学与分子生物学系.宁波大学医学部.2024-10-08
郭俊明:医学是终身学习的学科.宁波大学医学部基础医学院.2024-10-08
学校简介.宁波大学研究生院.2024-10-08