孙铁民,男,出生于1958年10月,农安县人,1981年毕业于沈阳药科大学,沈阳药科大学药物化学国家精品课负责人。

工作经历

教育经历

科研方向

论文

An efficient, scalable and eco‐friendly synthesis of 4,5‐substituted 吡咯‐3‐carbonitriles by intramolecular annulation on Pd/C and HZSM-5[J]. ChemCatChem, 2019.

Increasing the Purity of Lafutidine Using a “Suicide Substrate”[J].Organic Process Research \u0026 Development, 2018, 22(9): 1081-1085.

Spectroscopic investigations and molecular docking analysis of ML115: A potential molecular probe of the signal transducer and activator of transcription[J]. Journal of Molecular Structure, 2019, 1175: 638-647.

A Class of Amide Ligands Enable Catalyzed Coupling of (Hetero) aryl Halides with Sulfinic Acid Salts under Mild Conditions[J]. The Journal of organic 化学, 2018.

Theoretical studies on the mechanism of sugammadex for the reversal of aminosteroid-induced neuromuscular blockade[J]. Journal of Molecular Liquids, 2018 .

Conformational and characterization of benidipine 氯化氢 polymorphs: Spectroscopic and computational modeling investigations[J]. Journal of 摩尔ecular Structure, 2018, 1164: 493-500.

设计, Synthesis, Configuration Research, and In Vitro Antituberculosis Activities of two Chiral Naphthylamine Substituted Analogs of Bedaquiline[J]. Journal of Heterocyclic 化学, 2017, 54(2): 1024-1030.

Conformations and interactions in pasiniazid: a spectroscopic and computational characterization[J]. Journal of Molecular Structure, 2017, 1133: 179-186.

Effectively enhancing the enantioseparation ability of β-cyclodextrin derivatives by de novo 设计 and molecular modeling[J]. Analyst, 2017, 142(19): 3699-3706.

Determination of absolute configuration of an isopimarane-type diterpenoid by experimental and theoretical electronic circular dichroism and vibrational circular dichroism[J]. Journal of Molecular Structure, 2017, 1146: 484-489.

设计 and Stereochemical Research (DFT, ECD and 晶体 Structure) of Novel Bedaquiline Analogs as Potent Antituberculosis Agents[J]. Molecules, 2016, 21(7): 875.

The 立体化学 of baishouwubenzophenone, a unique atropisomer from C. wilfordii[J]. Journal of Molecular Structure, 2016, 1125: 370-373.

Detailed structural study of β-artemether: 密度 functional theory (DFT) calculations of infrared, Raman spectroscopy, and vibrational circular dichroism[J]. Journal of Molecular Structure, 2015, 1097: 61-68.

An Electronic Circular Dichroism Study for the Structure–Chiroptical Relationship of Chiral Proton Pump Inhibitors[J].化学 Letters, 2015, 45(2): 110-112.

Synthesis, 晶体 Structure, Absolute Configuration and Antitumor Activity of the Enantiomers of 5-2-chloro-N-(1-phenylethyl) 吡啶3-sulfon酰胺[J]. Molecules, 2015, 20(11): 20926-20938.

设计 and optimization of novel 4-(2-fluorophenoxy) quinoline derivatives bearing a hydrazone moiety as c-Met kinase inhibitors[J]. European journal of medicinal 化学, 2014, 87: 508-518.

Organic Process Research \u0026 Development

Journal of Molecular Structure

Journal of Heterocyclic Chemistry

Molecules

Journal of Molecular Structure

Journal of Molecular Structure

化学 Letters

Molecules

Stereochemical Investigation of a Novel Biological Active Substance from the Secondary Metabolites of Marine Fungus Penicillium chrysogenum SYP-F-2720[J]. Journal of the Mexican Chemical Society, 2015, 59(1): 53-58.

密度 functional theory (DFT) and natural bond orbital (NBO) study of vibrational spectra and intramolecular bond interaction of l-ornithin欧洲篮球联赛aspartate[J].Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015, 136: 338-346

The 立体化学 of two monoterpenoid diastereomers from Ferula dissecta[J]. RSC Advances, 2014, 4(28): 14373-14377.

Determination of Absolute Configurations of Bedaquiline Analogs by Quantum Chemical Electronic Circular Dichroism Calculations and an X‐射线 Diffraction Study[J]. European Journal of Organic Chemistry, 2014, 18(6):3814–3821.

Selective Substitution of 31/42–OH in Rapamycin Guided by an in Situ IR Technique[J]. Molecules, 2014, 19(6): 7770-7784.

设计 and optimization of novel 4-(2-fluorophenoxy) quinoline derivatives bearing a hydrazone moiety as c-Met kinase inhibitors[J]. European journal of medicinal 化学, 2014, 87: 508-518.

Study on molecular structure, spectroscopic investigation (IR, Raman and NMR), vibrational assignments and HOMO–LUMO analysis of L- folinate using DFT: A combined experimental and quantum chemical approach[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014, 120: 106118.

Phenolic Esters of O-Desmethylvenlafaxine with Improved Oral Bioavailability and Brain Uptake[J]. Molecules, 2013, 18(12): 14920-14934.

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